Transforming Growth Factorβ-Induced Superficial Zone Protein Accumulation in the Surface Zone of Articular Cartilage Is Dependent on the Cytoskeleton
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چکیده
منابع مشابه
Transforming growth factor β-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton.
The phenotype of articular chondrocytes is dependent on the cytoskeleton, specifically the actin microfilament architecture. Articular chondrocytes in monolayer culture undergo dedifferentiation and assume a fibroblastic phenotype. This process can be reversed by altering the actin cytoskeleton by treatment with cytochalasin. Whereas dedifferentiation has been studied on chondrocytes isolated f...
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ژورنال
عنوان ژورنال: Tissue Engineering Part A
سال: 2014
ISSN: 1937-3341,1937-335X
DOI: 10.1089/ten.tea.2013.0043